Leukocyte-Platelet Rich Fibrin

Platelets play a critical role in wound healing.   Dr. Maranon utilizes Leukocyte-Platelet Rich Fibrin (L-PRF) as an adjunct in many of his surgical procedures.  In the process, a patient’s own platelets are concentrated in a centrifuge.  These platelets contain viable cells and biologic mediators that include growth factors and cytokines that are beneficial and accelerate healing.  Obtaining L-PRF does not require any artificial biochemical modification and no foreign substances are added in the process.
Leukocyte-Platelet Rich Fibrin Beneficial outcomes:
  • Shown to help reduce bleeding even in patients on anticoagulant therapy

  • Enhances soft tissue healing and bone regeneration

  • Increases tissue vascularity

  • Not difficult to obtain and use

  • Beneficial in older patients that have advanced periodontal disease

  • Decreases the risk of dry sockets

  • Promising results when used in implant surgeries. Studies have shown strong positive results of the effect of L-PRF in implant surgeries specifically in:
    • Improved implant prognosis
    • Enhancing bone regeneration
    • Superior bone density after bone grafting
    • Increased new bone formation
  • Proposed in managing bisphosphonate-related osteonecrosis or avascular necrosis of the jaw